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Positive and negative influences of regulatory T cells on tumour immunity.

Abstract:

Clinicians and scientists have long questioned whether the immune system has a role in destroying cancerous tissue. Studies performed in animal models have, however, recently revealed that the immune system can, at least in principle, effectively control tumours. In parallel with these findings, a large body of evidence indicates that although the immune system has the capacity to control tumours, there are also regulatory mechanisms that subdue these responses. A major challenge of tumour im...

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Publication status:
Published

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Publisher copy:
10.1038/onc.2008.269

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Experimental Medicine Division, Molecular Medicine
Role:
Author
Journal:
Oncogene
Volume:
27
Issue:
45
Pages:
5886-5893
Publication date:
2008-10-05
DOI:
EISSN:
1476-5594
ISSN:
0950-9232
URN:
uuid:42c4e26a-22b1-4720-ab98-d2142f16354b
Source identifiers:
8551
Local pid:
pubs:8551

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