Fatal myocardial infarction and use of psychotropic drugs in young women.

Journal article

We have observed an unexpected 17-fold increase in risk of fatal [corrected] myocardial infarction (relative risk 16.9, 95% confidence interval 3.9-72.8) associated with current use of psychotropic drugs. This incidental finding, in a case-control study of cardiovascular mortality in women aged 16-39 not designed to test any hypothesis about psychotropic drugs, should be treated cautiously. There is, however, evidence of a relation between psychiatric morbidity and cardiovascular disease and the association recorded here requires further investigation.

Authors: Thorogood, M; Cowen, P; Mann, J; Murphy, M; Vessey, M

• Publication status: Published
• Journal: Lancet (London, England)
• Volume: 340
• Issue: 8827
• Pages: 1067-1068
• Publication date: 1992-10-01
• DOI: 10.1016/0140-6736(92)93081-w
• EISSN: 1474-547X
• ISSN: 0140-6736
• Language: English
• Keywords: Adolescent; Adult; Subarachnoid Hemorrhage; Thrombophlebitis; Great Britain; Case-Control Studies; Myocardial Infarction; Female; Risk Factors; Humans; Psychotropic Drugs