Journal article
Elimination of Latently HIV-infected Cells from Antiretroviral Therapy-suppressed Subjects by Engineered Immune-mobilizing T-cell Receptors.
- Abstract:
-
Persistence of human immunodeficiency virus (HIV) in a latent state in long-lived CD4+ T-cells is a major barrier to eradication. Latency-reversing agents that induce direct or immune-mediated cell death upon reactivation of HIV are a possible solution. However, clearance of reactivated cells may require immunotherapeutic agents that are fine-tuned to detect viral antigens when expressed at low levels. We tested the antiviral efficacy of immune-mobilizing monoclonal T-cell receptors against v...
Expand abstract
- Publication status:
- Published
- Peer review status:
- Peer reviewed
Actions
Access Document
- Files:
-
-
(Version of record, pdf, 2.8MB)
-
- Publisher copy:
- 10.1038/mt.2016.114
Why is the content I wish to access not available via ORA?
Bibliographic data (the information relating to research outputs) and full-text items (e.g. articles, theses, reports, etc.) arrive in ORA from several different sources. Unfortunately we are not able to make available the full-text for every research output.
Please contact the ORA team (
) if you have queries regarding unavailable content OR if you are aware of a full-text copy we can make available.
) if you have queries regarding unavailable content OR if you are aware of a full-text copy we can make available.
Content may be unavailable for the following four reasons
-
Version unsuitable
-
We have not obtained a suitable full-text for a given research output. See this page for more information.
-
Recently completed
-
Sometimes content is held in ORA but is unavailable for a fixed period of time to comply with the policies and wishes of rights holders.
-
Permissions
-
All content made available in ORA should comply with relevant rights, such as copyright. See this page for more information.
-
Clearance
-
Some thesis volumes scanned as part of the digitisation scheme funded by Dr Leonard Polonsky are currently unavailable due to sensitive material or uncleared third-party copyright content. We are attempting to contact authors whose theses are affected.
Alternative access to the full-text
You may be able to access the full-text directly from the publisher's website using the 'Publisher Copy' link in the 'Links & Downloads' box from a research output's ORA record page. This method may require an institutional or individual subscription to the journal/resource.
Authors
Funding
NIHR Oxford Biomedical Research Centre
More from this funder
Bibliographic Details
- Publisher:
- Nature Publishing Group Publisher's website
- Journal:
- Mol Ther Journal website
- Publication date:
- 2016-07-12
- Acceptance date:
- 2016-05-24
- DOI:
- EISSN:
-
1525-0024
- ISSN:
-
1525-0016
- Source identifiers:
-
633896
Item Description
- Language:
- English
- Pubs id:
-
pubs:633896
- UUID:
-
uuid:42207a3c-4604-4149-b94c-f83bdedfea0e
- Local pid:
- pubs:633896
- Deposit date:
- 2016-07-13
Terms of use
- Copyright holder:
- Yang et al
- Copyright date:
- 2016
- Notes:
- Author(s) retain copyright; published by Nature Publishing Group under license. Molecular Therapy is the official journal of the American Society of Gene and Cell Therapy. This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
If you are the owner of this record, you can report an update to it here: Report update to this record