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Analysis of FGGY as a risk factor for sporadic amyotrophic lateral sclerosis.

Abstract:

A genome-wide association study (GWAS) using pooled DNA samples from 386 sporadic ALS patients and 542 controls from the USA, identified genetic variation in FGGY (FLJ10986) as a risk factor, as well as 66 additional candidate SNPs. Considering the large number of hypotheses that are tested in GWAS, independent replication of associations is crucial for identifying true-positive genetic risk factors for disease. The primary aim of this study was to study the association between FGGY and spora...

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Publication status:
Published

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Publisher copy:
10.3109/17482960802673042

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Journal:
Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases
Volume:
10
Issue:
5-6
Pages:
441-447
Publication date:
2009-01-01
DOI:
EISSN:
1471-180X
ISSN:
1748-2968
URN:
uuid:420279b0-8c01-4f98-b43d-b514de0c358e
Source identifiers:
34979
Local pid:
pubs:34979

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