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Genetic and environmental determinants of violence risk in psychotic disorders: a multivariate quantitative genetic study of 1.8 million Swedish twins and siblings

Abstract:

Patients diagnosed with psychotic disorders (for example, schizophrenia and bipolar disorder) have elevated risks of committing violent acts, particularly if they are comorbid with substance misuse. Despite recent insights from quantitative and molecular genetic studies demonstrating considerable pleiotropy in the genetic architecture of these phenotypes, there is currently a lack of large-scale studies that have specifically examined the aetiological links between psychotic disorders and vio...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1038/mp.2015.184

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, Psychiatry
Larsson, HL More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Psychiatry
Swedish Council for Working Life and Social Research More from this funder
More from this funder
Grant:
2010–3184; 2011–2492; 2013–5867
Publisher:
Nature Publishing Group: Open Access Hybrid Model Option B Publisher's website
Journal:
Molecular Psychiatry Journal website
Publication date:
2015-12-15
DOI:
EISSN:
1476-5578
ISSN:
1359-4184
URN:
uuid:41f64835-e36e-406a-a6fd-053316ff95b0
Source identifiers:
580110
Local pid:
pubs:580110

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