Numerical simulation of microcarrier motion in a rotating wall vessel bioreactor.

Journal article

OBJECTIVE: To analyze the forces of rotational wall vessel (RWV) bioreactor on small tissue pieces or microcarrier particles and to determine the tracks of microcarrier particles in RWV bioreactor. METHODS: The motion of the microcarrier in the rotating wall vessel (RWV) bioreactor with both the inner and outer cylinders rotating was modeled by numerical simulation. RESULTS: The continuous trajectory of microcarrier particles, including the possible collision with the wall was obtained. An e...

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Authors: Ju, Z; Liu, T; Ma, X; Cui, Z

• Publication status: Published
• Journal: Biomedical and environmental sciences : BES
• Volume: 19
• Issue: 3
• Pages: 163-168
• Publication date: 2006-06-01
• ISSN: 0895-3988
• Language: English
• Keywords: Bioreactors; Motion; Microspheres; Tissue Engineering; Computer Simulation; Rheology; Porosity; Rotation; Stress, Mechanical