- Abstract:
-
Recent work on the MACPF/CDC superfamily of pore-forming proteins has focused on the structural analysis of monomers and pore-forming oligomeric complexes. We set the family of proteins in context and highlight aspects of their function which the direct and exclusive equation of oligomers with pores fails to explain. Starting with a description of the distribution of MACPF/CDC proteins across the domains of life, we proceed to show how their evolutionary relationships can be understood on the...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1007/s00018-012-1153-8
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- Journal:
- Cellular and molecular life sciences : CMLS
- Volume:
- 70
- Issue:
- 12
- Pages:
- 2083-2098
- Publication date:
- 2013-06-05
- DOI:
- EISSN:
-
1420-9071
- ISSN:
-
1420-682X
- URN:
-
uuid:41aa0f5d-137f-4591-beab-f9ee242bfc68
- Source identifiers:
-
352415
- Local pid:
- pubs:352415
- Copyright date:
- 2013
Journal article
Effects of MACPF/CDC proteins on lipid membranes.
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