Conference item
A brain metastasis therapy tweak, for the better? Concomitant stereotactic radiotherapy and molecular-targeted therapy
- Abstract:
- The most common cause of cancer demise is the metastasis to distant organs. In particular, brain metastasis represents one of the highest mortality rates in the oncology field. Some of the reasons for the meagre advance in the treatment of this disease are the limited conditions for favourable surgical debulking of tumour, off-target effects of conventional treatments and the limited efficacy of delivery into the brain for currently available drugs. Contrary to those conventional strategies, targeted anticancer therapies exploit molecules that act on specific mechanisms that may disturb the malignant process, whilst minimising adverse effects on healthy tissues. Based on that approach, we have been working on novel anti-cell adhesion molecule (CAM) therapies.
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Access Document
- Files:
-
-
(Preview, Accepted manuscript, pdf, 212.0KB, Terms of use)
-
- Publisher copy:
- 10.1093/neuonc/now292.008
Authors
- Publisher:
- Oxford University Press
- Host title:
- Neuro-Oncology
- Journal:
- 2016 British Neuro-Oncology Society Meeting (BNOS 2016) More from this journal
- Volume:
- 19
- Pages:
- 126
- Publication date:
- 2017-03-02
- Acceptance date:
- 2016-06-27
- DOI:
- EISSN:
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1523-5866
- ISSN:
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1522-8517
- Pubs id:
-
pubs:719630
- UUID:
-
uuid:41a21992-b867-4671-a907-3a77bdc09c9c
- Local pid:
-
pubs:719630
- Source identifiers:
-
719630
- Deposit date:
-
2018-10-30
- ARK identifier:
Terms of use
- Copyright holder:
- Soto et al
- Copyright date:
- 2017
- Notes:
- © The Author(s) 2017. Published by Oxford University Press on behalf of the Society for Neuro-Oncology. All rights reserved. For permissions, please e-mail: [email protected]. This abstract was presented at the 2016 British Neuro-Oncology Society Meeting (BNOS 2016). This is the accepted manuscript version of the abstract. The final version is available online from Oxford University Press at: https://doi.org/10.1093/neuonc/now292.008
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