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A brain metastasis therapy tweak, for the better? Concomitant stereotactic radiotherapy and molecular-targeted therapy

Abstract:

The most common cause of cancer demise is the metastasis to distant organs. In particular, brain metastasis represents one of the highest mortality rates in the oncology field. Some of the reasons for the meagre advance in the treatment of this disease are the limited conditions for favourable surgical debulking of tumour, off-target effects of conventional treatments and the limited efficacy of delivery into the brain for currently available drugs. Contrary to those conventional strategies, ...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted manuscript

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Publisher copy:
10.1093/neuonc/now292.008

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More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Oncology
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Oncology
Subgroup:
CRUK/MRC Ox Inst Radiation Oncology
Role:
Author
ORCID:
0000-0002-4169-8447
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Oncology
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Oncology
Subgroup:
CRUK/MRC Ox Inst Radiation Oncology
Role:
Author
ORCID:
0000-0003-1211-2766
Publisher:
Oxford University Press Publisher's website
Volume:
19
Pages:
126
Publication date:
2017-03-02
Acceptance date:
2016-06-27
DOI:
EISSN:
1523-5866
ISSN:
1522-8517
Pubs id:
pubs:719630
URN:
uri:41a21992-b867-4671-a907-3a77bdc09c9c
UUID:
uuid:41a21992-b867-4671-a907-3a77bdc09c9c
Local pid:
pubs:719630

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