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Journal article

A "reverse pharmacology" approach for developing an anti-malarial phytomedicine.

Abstract:

A "reverse pharmacology" approach to developing an anti-malarial phytomedicine was designed and implemented in Mali, resulting in a new standardized herbal anti-malarial after six years of research. The first step was to select a remedy for development, through a retrospective treatment-outcome study. The second step was a dose-escalating clinical trial that showed a dose-response phenomenon and helped select the safest and most efficacious dose. The third step was a randomized controlled tri...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1186/1475-2875-10-s1-s8

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Primary Care Health Sciences
Role:
Author
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Department of Primary Health Care, University of Oxford More from this funder
Swiss Agency for Development and Cooperation More from this funder
Publisher:
BioMed Central Publisher's website
Journal:
Malaria Journal Journal website
Volume:
10
Issue:
Suppl. 1
Article number:
S8
Publication date:
2011-01-01
DOI:
EISSN:
1475-2875
ISSN:
1475-2875
Source identifiers:
124382
Language:
English
Keywords:
UUID:
uuid:417c7a4c-3cc7-4de1-918f-d6d6a9d93078
Local pid:
pubs:124382
Deposit date:
2012-12-19

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