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Involvement of genes of genome maintenance in the regulation of phase variation frequencies in Neisseria meningitidis.

Abstract:

In Neisseria meningitidis, the reversible expression of surface antigens, i.e. phase variation, results from changes within repeated simple sequence motifs located in coding or promoter regions of the genes involved in their biosynthesis. The mutation rates of these simple sequences, which have a major influence on the generation of phenotypic diversity, can affect the fitness of the population. The aim of the present study was to investigate the involvement of genetic factors involved (mutS ...

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Publication status:
Published

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Publisher copy:
10.1099/mic.0.27182-0

Authors


Journal:
Microbiology (Reading, England)
Volume:
150
Issue:
Pt 9
Pages:
3001-3012
Publication date:
2004-09-01
DOI:
EISSN:
1465-2080
ISSN:
1350-0872
Source identifiers:
115607

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