Poor sleep quality is associated with increased cortical atrophy in community-dwelling adults.

Journal article

OBJECTIVE: To examine the relationship between sleep quality and cortical and hippocampal volume and atrophy within a community-based sample, explore the influence of age on results, and assess the possible confounding effects of physical activity levels, body mass index (BMI), and blood pressure. METHODS: In 147 community-dwelling adults (92 female; age 53.9 ± 15.5 years), sleep quality was measured using the Pittsburgh Sleep Quality Index and correlated with cross-sectional measures of volu...

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Authors: Sexton, C; Storsve, AB; Walhovd, K; Johansen-Berg, H; Fjell, A

• Publication status: Published
• Journal: Neurology
• Volume: 83
• Issue: 11
• Pages: 967-973
• Publication date: 2014-09-01
• DOI: 10.1212/wnl.0000000000000774
• EISSN: 1526-632X
• ISSN: 0028-3878
• Language: English
• Keywords: Hippocampus; Longitudinal Studies; Adult; Age Factors; Magnetic Resonance Imaging; Male; Organ Size; Young Adult; Brain Diseases; Humans; Female; Exercise; Middle Aged; Residence Characteristics; Cerebral Cortex; Sleep Initiation and Maintenance Disorders; Atrophy; Blood Pressure; Cross-Sectional Studies; Body Mass Index; Aged, 80 and over; Aged