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Chemical modification of proteins at cysteine: opportunities in chemistry and biology.

Abstract:

Chemical modification of proteins is a rapidly expanding area in chemical biology. Selective installation of biochemical probes has led to a better understanding of natural protein modification and macromolecular function. In other cases such chemical alterations have changed the protein function entirely. Additionally, tethering therapeutic cargo to proteins has proven invaluable in campaigns against disease. For controlled, selective access to such modified proteins, a unique chemical handl...

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Publication status:
Published

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Publisher copy:
10.1002/asia.200800427

Authors


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Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Organic Chemistry
Role:
Author
Journal:
Chemistry, an Asian journal
Volume:
4
Issue:
5
Pages:
630-640
Publication date:
2009-05-01
DOI:
EISSN:
1861-471X
ISSN:
1861-4728
Language:
English
Keywords:
Pubs id:
pubs:34618
UUID:
uuid:405c4fe5-c923-490e-810a-b1ca9b07e408
Local pid:
pubs:34618
Source identifiers:
34618
Deposit date:
2012-12-19

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