Journal article
A refined model for the TSG-6 link module in complex with hyaluronan: use of defined oligosaccharides to probe structure and function.
- Abstract:
-
Tumor necrosis factor-stimulated gene-6 (TSG-6) is an inflammation-associated hyaluronan (HA)-binding protein that contributes to remodeling of HA-rich extracellular matrices during inflammatory processes and ovulation. The HA-binding domain of TSG-6 consists solely of a Link module, making it a prototypical member of the superfamily of proteins that interacts with this high molecular weight polysaccharide composed of repeating disaccharides of D-glucuronic acid and N-acetyl-D-glucosamine (Gl...
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- Publication status:
- Published
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Bibliographic Details
- Journal:
- Journal of biological chemistry
- Volume:
- 289
- Issue:
- 9
- Pages:
- 5619-5634
- Publication date:
- 2014-02-01
- DOI:
- EISSN:
-
1083-351X
- ISSN:
-
0021-9258
- Source identifiers:
-
445863
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:445863
- UUID:
-
uuid:404384b1-132a-49ab-862c-efa6b64e2542
- Local pid:
- pubs:445863
- Deposit date:
- 2014-02-08
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- Copyright date:
- 2014
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