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Journal article

Syncytiotrophoblast derived extracellular vesicles in relation to pre-eclampsia

Abstract:

The syncytiotrophoblast, a fused single-cell layer between mother and fetus, constitutively releases extracellular vesicles (STBEV) directly into the maternal circulation. STBEV contain a variety of proteins and RNA which can be targeted to specific cells. In preeclampsia, asymptomatic placental oxidative stress is a precursor to later multi-organ dysfunction in the mother. Increased STBEV release in preeclampsia is considered a manifestation of syncytiotrophoblast stress, which may play a ke...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1097/fm9.0000000000000093

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Women's & Reproductive Health
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Women's & Reproductive Health
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Women's & Reproductive Health
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Women's & Reproductive Health
Role:
Author
ORCID:
0000-0002-6012-2574
Publisher:
Lippincott, Williams & Wilkins Publisher's website
Journal:
Maternal-Fetal Medicine Journal website
Volume:
3
Issue:
2
Pages:
151-160
Publication date:
2021-02-05
Acceptance date:
2021-01-31
DOI:
EISSN:
2641-5895
ISSN:
2641-5895
Language:
English
Keywords:
Pubs id:
1163537
Local pid:
pubs:1163537
Deposit date:
2021-02-26

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