Population genomics of Escherichia coli in livestock-keeping households across a rapidly developing urban landscape

Journal article

Antimicrobial resistance (AMR) is a significant and growing threat to human health. A recent United Nations General Assembly declaration highlights that those in need must have sustained access to effective treatments. In the absence of a reliable supply of new drugs, pressure on existing drugs can be reduced by minimising demand. Routes to reducing demand include: promotion of WASH (access to clean water, sanitation and hygiene) and Universal Health Coverage (UHC); improved infection control in health care settings; and continued efforts to curtail drug use in agriculture. This is a One Health strategy, requiring coordinated action across the human, livestock and environmental sectors.

Authors: Muloi, DM; Wee, BA; McClean, DMH; Ward, MJ; Pankhurst, L

• Publication status: Published
• Peer review status: Peer reviewed
• Publisher: Nature Research
• Journal: Nature Microbiology
• Volume: 7
• Issue: 4
• Pages: 581-589
• Publication date: 2022-03-14
• DOI: 10.1038/s41564-022-01079-y
• EISSN: 2058-5276
• ISSN: 2058-5276
• Language: English
• Keywords: Medicine; Ecology; Gene; Population; Escherichia coli; Genomics; Biology; Resistome; Host (biology); Wildlife; Genetics; Genome; Bacteria; Environmental health; Antibiotic resistance; Livestock