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Journal article

Fasting plasma insulin concentrations are associated with changes in hepatic fatty acid synthesis and partitioning prior to changes in liver fat content in healthy adults

Abstract:

Resistance to the action of insulin impacts on fatty acid delivery to the liver, fatty acid synthesis and oxidation within the liver and triglyceride export from the liver. To understand the metabolic consequences of hepatic fatty acid synthesis, partitioning, oxidation and net liver fat content in the fasted and postprandial states we studied healthy men and women with varying degrees of insulin resistance before and after consumption of a mixed meal using stable-isotope tracer methodologies...

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Publication status:
Published
Peer review status:
Peer reviewed

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Files:
Publisher copy:
10.2337/db16-0236

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
OCDEM
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
OCDEM
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
RDM Cardiovascular Medicine
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
OCDEM
Role:
Author
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Publisher:
American Diabetes Association Publisher's website
Journal:
Diabetes Journal website
Volume:
65
Issue:
7
Pages:
1858-1867
Publication date:
2016-07-01
Acceptance date:
2016-04-14
DOI:
EISSN:
1939-327X
ISSN:
1099-0895
Source identifiers:
616163
Pubs id:
pubs:616163
UUID:
uuid:3f93d1ae-6537-4cb9-a0c4-fe2d1335a9b8
Local pid:
info:fedora/pubs:616163
Deposit date:
2016-09-07

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