The basic helix-loop-helix transcription factor, Tal2, marks the lateral floor plate of the spinal cord in zebrafish.

Journal article

Basic helix-loop-helix (bHLH) transcription factors play key roles in the development of the central nervous system. Here we report the isolation of a zebrafish gene that encodes a homologue of the mammalian bHLH transcription factor, Tal2. In zebrafish embryos, tal2, like its mammalian homologue, is strongly expressed in the diencephalon and the mesencephalon, with the latter expression located in post-mitotic cells of the tectum. However, in addition to this conserved brain expression, we a...

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Authors: Pinheiro, P; Gering, M; Patient, R

• Publication status: Published
• Journal: Gene expression patterns : GEP
• Volume: 4
• Issue: 1
• Pages: 85-92
• Publication date: 2004-01-01
• DOI: 10.1016/s1567-133x(03)00145-5
• EISSN: 1872-7298
• ISSN: 1567-133X
• Language: English
• Keywords: Amino Acid Sequence; Animals; Sequence Homology, Amino Acid; Zebrafish Proteins; Gene Expression Regulation, Developmental; Time Factors; Gene Expression Profiling; Zebrafish; Embryonic Development; In Situ Hybridization; Genetic Markers; Spinal Cord; Molecular Sequence Data; Transcription Factors; Basic Helix-Loop-Helix Transcription Factors; Embryo, Nonmammalian