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L-arginine effects on Na+ transport in M-1 mouse cortical collecting duct cells--a cationic amino acid absorbing epithelium.

Abstract:

The effect of L-arginine on transepithelial ion transport was examined in cultured M-1 mouse renal cortical collecting duct (CCD) cells using continuous short circuit current (Isc) measurements in HCO3-/CO2 buffered solution. Steady state Isc averaged 73.8 +/- 3.2 microA/cm2 (n = 126) and was reduced by 94 +/- 0.6% (n = 16) by the apical addition of 100 microM amiloride. This confirms that the predominant electrogenic ion transport in M-1 cells is Na+ absorption via the epithelial sodium chan...

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Publisher copy:
10.1007/s002320010063

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Journal:
The Journal of membrane biology
Volume:
180
Issue:
2
Pages:
111-121
Publication date:
2001-03-05
DOI:
EISSN:
1432-1424
ISSN:
0022-2631
URN:
uuid:3f539d29-3116-4a7c-b3dc-0a84c7998621
Source identifiers:
113558
Local pid:
pubs:113558

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