Journal article : Review
Cooperation and interplay between EGFR signalling and extracellular vesicle biogenesis in cancer
- Abstract:
-
Epidermal growth factor receptor (EGFR) takes centre stage in carcinogenesis throughout its entire cellular trafficking odyssey. When loaded in extracellular vesicles (EVs), EGFR is one of the key proteins involved in the transfer of information between parental cancer and bystander cells in the tumour microenvironment. To hijack EVs, EGFR needs to play multiple signalling roles in the life cycle of EVs. The receptor is involved in the biogenesis of specific EV subpopulations, it signals as a...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Authors
Funding
Biotechnology and Biological Sciences Research Council
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Bibliographic Details
- Publisher:
- MDPI Publisher's website
- Journal:
- Cells Journal website
- Volume:
- 9
- Issue:
- 12
- Article number:
- 2639
- Publication date:
- 2020-12-08
- Acceptance date:
- 2020-12-02
- DOI:
- EISSN:
-
2073-4409
- Pmid:
-
33302515
Item Description
- Language:
- English
- Keywords:
- Subtype:
- Review
- Pubs id:
-
1151461
- Local pid:
- pubs:1151461
- Deposit date:
- 2021-02-10
Terms of use
- Copyright holder:
- LC Zanetti-Domingues et al.
- Copyright date:
- 2020
- Rights statement:
- © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
- Licence:
- CC Attribution (CC BY)
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