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Programing the formation of DNA and PNA quadruplexes by pi-pi-stacking interactions.

Abstract:
Guanine (G) rich G(4)T(4)G(4) DNA and homologous PNA strands tend to form antiparallel dimeric quadruplexes. In contrast, the same DNA strands carrying planar aromatic 5'-residues preferentially form parallel DNA quadruplex. Conformation and composition of the DNA quadruplexes can be programed by pi-pi-stacking interaction exerted by the 5'-residues.
Publication status:
Published

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Publisher copy:
10.1039/b915955j

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Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Organic Chemistry
Role:
Author
Journal:
Chemical Communications
Volume:
46
Issue:
10
Pages:
1685-1687
Publication date:
2010-03-01
DOI:
EISSN:
1364-548X
ISSN:
1359-7345
Source identifiers:
117490
Language:
English
Keywords:
Pubs id:
pubs:117490
UUID:
uuid:3f1dd407-e3a0-4945-aa3c-225c8a818686
Local pid:
pubs:117490
Deposit date:
2012-12-19

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