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Journal article

Simulations for designing and interpreting intervention trials in infectious diseases

Abstract:

Background

Interventions in infectious diseases can have both direct effects on individuals who receive the intervention as well as indirect effects in the population. In addition, intervention combinations can have complex interactions at the population level, which are often difficult to adequately assess with standard study designs and analytical methods.

Discussion

Herein, we urge the adoption of a new paradigm for the design and interpretation of intervention...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1186/s12916-017-0985-3

Authors


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ORCID:
0000-0002-3127-1757
Auranen, K More by this author
Bellan, SE More by this author
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Publisher:
BioMed Central Publisher's website
Journal:
BMC Medicine Journal website
Volume:
15
Issue:
1
Pages:
223
Publication date:
2017-12-29
Acceptance date:
2017-12-05
DOI:
EISSN:
1741-7015
ISSN:
1741-7015
Pubs id:
pubs:817185
URN:
uri:3f0b1d1e-8495-4489-872c-c8cfc76ce5b4
UUID:
uuid:3f0b1d1e-8495-4489-872c-c8cfc76ce5b4
Local pid:
pubs:817185

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