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The effects of NMDA-induced retrohippocampal lesions on performance of four spatial memory tasks known to be sensitive to hippocampal damage in the rat.

Abstract:

Four separate cohorts of rats were employed to examine the effects of cytotoxic retrohippocampal lesions in four spatial memory tasks which are known to be sensitive to direct hippocampal damage and/or fornix-fimbria lesions in the rat. Selective retrohippocampal lesions were made by means of multiple intracerebral infusions of NMDA centred on the entorhinal cortex bilaterally. Cell damage typically extended from the lateral entorhinal area to the distal ventral subiculum. Experiment 1 demons...

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Publication status:
Published

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Authors


Gubler, MK More by this author
Broersen, L More by this author
Veenman, CL More by this author
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Journal:
The European journal of neuroscience
Volume:
11
Issue:
1
Pages:
123-140
Publication date:
1999-01-05
DOI:
EISSN:
1460-9568
ISSN:
0953-816X
URN:
uuid:3f012de9-49cf-4977-8a89-8145f1a7c289
Source identifiers:
310881
Local pid:
pubs:310881

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