The Pdx1 or Ipf1 gene encodes an important homeodomain-containing protein with key roles in pancreas development and function. Mutations in human PDX1 are implicated in developmental defects and disease of the pancreas. Extensive research, including genome sequencing, has indicated that Pdx1 is the only member of its gene family in mammals, birds, amphibians, and ray-finned fish, and with the exception of teleost fish, this gene forms part of the ParaHox ge...Expand abstract
- Publication status:
- Peer review status:
- Peer reviewed
- Publisher's version
- Oxford University Press Publisher's website
- Molecular biology and evolution Journal website
- Publication date:
- Source identifiers:
- Local pid:
- Copyright holder:
- John F. Mulley and Peter W. H. Holland
- Copyright date:
- Copyright © 2010 John F. Mulley and Peter W. H. Holland. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution.This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.5), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Parallel retention of Pdx2 genes in cartilaginous fish and coelacanths.
If you are the owner of this record, you can report an update to it here: Report update to this record