Dopamine modulates risk-taking as a function of baseline sensation-seeking trait.

Journal article

Trait sensation-seeking, defined as a need for varied, complex, and intense sensations, represents a relatively underexplored hedonic drive in human behavioral neuroscience research. It is related to increased risk for a range of behaviors including substance use, gambling, and risky sexual practice. Individual differences in self-reported sensation-seeking have been linked to brain dopamine function, particularly at D2-like receptors, but so far no causal evidence exists for a role of dopami...

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Authors: Norbury, A; Manohar, S; Rogers, R; Husain, M

• Publication status: Published
• Journal: Journal of neuroscience : the official journal of the Society for Neuroscience
• Volume: 33
• Issue: 32
• Pages: 12982-12986
• Publication date: 2013-08-01
• DOI: 10.1523/jneurosci.5587-12.2013
• EISSN: 1529-2401
• ISSN: 0270-6474
• Language: English
• Keywords: Probability; Choice Behavior; Double-Blind Method; Humans; Self Report; Adult; Dopamine Antagonists; Memory, Short-Term; Dopamine; Domperidone; Games, Experimental; Decision Making; Sensation; Analysis of Variance; Ergolines; Risk-Taking; Individuality; Dopamine Agonists; Young Adult; Female