- Abstract:
-
Comprehensive analysis of the gene expression profiles associated with human monocyte-to-macrophage differentiation and polarization toward M1 or M2 phenotypes led to the following main results: 1) M-CSF-driven monocyte-to-macrophage differentiation is associated with activation of cell cycle genes, substantiating the underestimated proliferation potential of monocytes. 2) M-CSF leads to expression of a substantial part of the M2 transcriptome, suggesting that under homeostatic conditions a d...
Expand abstract - Publication status:
- Published
- Journal:
- Journal of immunology (Baltimore, Md. : 1950)
- Volume:
- 177
- Issue:
- 10
- Pages:
- 7303-7311
- Publication date:
- 2006-11-05
- DOI:
- EISSN:
-
1550-6606
- ISSN:
-
0022-1767
- URN:
-
uuid:3ecbc349-b637-44f6-82a4-7dd7c467c10d
- Source identifiers:
-
21736
- Local pid:
- pubs:21736
- Language:
- English
- Keywords:
- Copyright date:
- 2006
Journal article
Transcriptional profiling of the human monocyte-to-macrophage differentiation and polarization: new molecules and patterns of gene expression.
Actions
Authors
Bibliographic Details
Item Description
Terms of use
Metrics
Altmetrics
Dimensions
If you are the owner of this record, you can report an update to it here: Report update to this record