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Blood pressure and arterial stiffness in Kenyan adolescents with α+thalassemia

Abstract:
Background Recent studies have discovered that α‐globin is expressed in blood vessel walls where it plays a role in regulating vascular tone. We tested the hypothesis that blood pressure (BP) might differ between normal individuals and those with α+thalassemia, in whom the production of α‐globin is reduced. gMethods and Results The study was conducted in Nairobi, Kenya, among 938 adolescents aged 11 to 17 years. Twenty‐four‐hour ambulatory BP monitoring and ... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1161/JAHA.117.005613

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ORCID:
0000-0003-1267-6422
Khayeka-Wandabwa, C More by this author
Muthumbi, E More by this author
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Wellcome Trust More from this funder
Publisher:
American Heart Association Publisher's website
Journal:
Journal of the American Heart Association Journal website
Volume:
6
Issue:
4
Pages:
Article: e005613
Publication date:
2017-04-05
Acceptance date:
2017-03-01
DOI:
ISSN:
2047-9980
Pubs id:
pubs:894048
URN:
uri:3ec65440-ccd9-4b90-9ab0-e8e7005138fd
UUID:
uuid:3ec65440-ccd9-4b90-9ab0-e8e7005138fd
Local pid:
pubs:894048

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