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Journal article

CETP gene variants and risk of vascular and non-vascular diseases in ~150,000 Chinese adults

Abstract:

Importance

Raising HDL-cholesterol through pharmacological inhibition of cholesteryl ester transfer protein is a potentially important strategy for prevention and treatment of cardiovascular diseases.

Objective

To use genetic variants in the CETP gene to assess potential risks and benefits of lifelong lower cholesteryl ester transfer protein activity on cardiovascular diseases and other outcomes.

Design

A prospective biobank study, with 9-year foll...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's Version

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Publisher copy:
10.1001/jamacardio.2017.4177

Authors


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Department:
Oxford, MSD, Nuffield Dept of Population Health, Clinical Trial Service Unit
More by this author
Department:
Oxford, MSD, Nuffield Dept of Population Health, Clinical Trial Service Unit
More by this author
Department:
Oxford, MSD, Nuffield Dept of Population Health, Clinical Trial Service Unit
More by this author
Department:
Oxford, MSD, Nuffield Dept of Population Health, Clinical Trial Service Unit
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Kadoorie Charitable Foundation More from this funder
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Grant:
202922/Z/16/Z
088158/Z/09/Z
104085/Z/14/Z
Chinese Ministry of Science and Technology More from this funder
National Natural Science Foundation of China More from this funder
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Publisher:
American Medical Association Publisher's website
Journal:
JAMA Cardiology Journal website
Volume:
3
Issue:
1
Pages:
34-43
Publication date:
2017-11-15
Acceptance date:
2017-09-21
DOI:
EISSN:
2380-6591
ISSN:
2380-6583
Pubs id:
pubs:730590
URN:
uri:3ec114de-b84e-4e4c-a9bb-c462f7708a47
UUID:
uuid:3ec114de-b84e-4e4c-a9bb-c462f7708a47
Local pid:
pubs:730590

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