Journal article
Regulation of expression of human RNA polymerase II-transcribed snRNA genes
- Abstract:
- In addition to protein-coding genes, RNA polymerase II (pol II) transcribes numerous genes for non-coding RNAs, including the small-nuclear (sn)RNA genes. snRNAs are an important class of non-coding RNAs, several of which are involved in pre-mRNA splicing. The molecular mechanisms underlying expression of human pol II-transcribed snRNA genes are less well characterized than for protein-coding genes and there are important differences in expression of these two gene types. Here, we review the DNA features and proteins required for efficient transcription of snRNA genes and co-transcriptional 3' end formation of the transcripts.
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Preview, Version of record, pdf, 716.7KB, Terms of use)
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- Publisher copy:
- 10.1098/rsob.170073
Authors
+ Conselho Nacional de Desenvolvimento Científico e Tecnológico
More from this funder
- Funding agency for:
- Guiro, J
- Grant:
- 201323/2015-0
- Publisher:
- Royal Society
- Journal:
- Open biology More from this journal
- Volume:
- 7
- Pages:
- 170073
- Publication date:
- 2017-06-14
- Acceptance date:
- 2017-05-11
- DOI:
- ISSN:
-
2046-2441
- Pmid:
-
28615474
- Language:
-
English
- Keywords:
- Pubs id:
-
pubs:702289
- UUID:
-
uuid:3e9fcd9c-a024-4eaa-9bdd-de73009320d1
- Local pid:
-
pubs:702289
- Source identifiers:
-
702289
- Deposit date:
-
2017-09-06
Terms of use
- Copyright holder:
- © 2017 Guiro and Murphy
- Copyright date:
- 2017
- Notes:
- Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/, which permits unrestricted use, provided the original author and source are credited.
- Licence:
- CC Attribution (CC BY)
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