The influence of insulin resistance on CSF and plasma biomarkers of Alzheimer’s pathology
Background: Insulin resistance (IR) has previously been associated with an increased risk of developing Alzheimer’s disease (AD), though the relationship between IR and AD is not yet clear. Here, we examined the influence of IR on AD by using plasma and cerebrospinal fluid (CSF) biomarkers related to IR and AD in cognitively healthy men, and to characterize the shared protein signatures between IR and AD.Expand abstract
Methods: 58 cognitively healthy men, 28 IR and 30 non-IR (age and APOE ε4 mat...
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- Peer reviewed
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- BioMed Central Publisher's website
- Alzheimer's Research and Therapy Journal website
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- Copyright holder:
- Westwood et al.
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- © The Author(s) 2017. Open Access: This article is distributed under the terms of the Creative Commons Attribution 4.0 International License.
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