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PRACTICAL SYNTHESIS OF DEOXYMANNOJIRIMYCIN AND MANNONOLACTAM FROM L-GULONOLACTONE - SYNTHESIS OF L-DEOXYMANNOJIRIMYCIN AND L-MANNONOLACTAM FROM D-GULONOLACTONE

Abstract:
An eight step synthesis of deoxymannojirimycin from L-gulonolactone in 25% overall yield is reported the key step is the formation of a δ-lactam by the reduction of a 5-azidolactone. The preparations of mannonolactam front L-gulonolactone and of L-deoxymannojirimycin and L-mannonolactam from D-gulonolactone are described. © 1989.
Publication status:
Published

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Journal:
TETRAHEDRON
Volume:
45
Issue:
1
Pages:
319-326
Publication date:
1989-01-01
DOI:
ISSN:
0040-4020
URN:
uuid:3e581a68-82a5-4f75-a334-8412d3070cb1
Source identifiers:
43243
Local pid:
pubs:43243
Language:
English

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