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Robust Capon beamforming for passive cavitation mapping during high-intensity focused ultrasound therapy.

Abstract:
A passive method that uses time exposure acoustics (TEA) to map inertial cavitation activity in real time during therapeutic ultrasound exposure was recently presented [Gyongy and Coussios, IEEE Trans. Biomed. Eng. 57, 48-56 (2010)]. While this approach provides sub-millimetric spatial resolution transversely to the high-intensity focused ultrasound (HIFU) beam, its axial resolution requires improvement. Furthermore, the TEA method is expected to have a lower overall resolution and diminished ability to reject interference and noise compared to an adaptive beamforming approach. To address these limitations, we propose the use of the adaptive, robust Capon beamformer (RCB), which has been previously shown in the context of active, 2-D ultrasound imaging to provide high resolution, good interference suppression, and robustness against steering vector errors. Using a multi-element tomographic cavitation sensor being developed for quality assessment of clinical HIFU transducers, the effectiveness of RCB is demonstrated for improved 3-D passive localization of inertial cavitation compared to TEA using simulated and experimental data.

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Publisher copy:
10.1121/1.3507982

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Institution:
University of Oxford
Division:
MPLS
Department:
Engineering Science
Role:
Author


Host title:
J Acoust Soc Am
Volume:
128
Issue:
4
Pages:
2280
Publication date:
2010-10-01
Event location:
United States
DOI:
ISSN:
1520-8524


Pubs id:
pubs:90808
UUID:
uuid:3e2ef38c-74d9-46c3-98b5-9c2c5f74f813
Local pid:
pubs:90808
Source identifiers:
90808
Deposit date:
2012-12-20
ARK identifier:

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