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DNA-guided DNA interference by a prokaryotic Argonaute

Abstract:: RNA interference is widely distributed in eukaryotes and has a variety of functions, including antiviral defence and gene regulation. All RNA interference pathways use small single-stranded RNA (ssRNA) molecules that guide proteins of the Argonaute (Ago) family to complementary ssRNA targets: RNA-guided RNA interference. The role of prokaryotic Ago variants has remained elusive, although bioinformatics analysis has suggested their involvement in host defence. Here we demonstrate that Ago of t...
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APA Style

Swarts, D., Jore, M., Westra, E., Zhu, Y., Janssen, J., Snijders, A., Wang, Y., Patel, D., Berenguer, J., Brouns, S., & Van Der Oost, J. (2014). DNA-guided DNA interference by a prokaryotic Argonaute. Nature, 507(7491), 258–261.

MLA Style

Swarts, D., et al. “DNA-Guided DNA Interference by a Prokaryotic Argonaute.” Nature, vol. 507, no. 7491, Nature Publishing Group, 2014, pp. 258–61.

Chicago Style

Swarts, D, M Jore, E Westra, Y Zhu, J Janssen, A Snijders, Y Wang, et al. 2014. “DNA-Guided DNA Interference by a Prokaryotic Argonaute.” Nature 507 (7491): 258–61.
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Publisher copy:: 10.1038/nature12971

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+ Swarts, D More by this author

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+ Jore, M More by this author

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+ Westra, E More by this author

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+ Zhu, Y More by this author

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+ Janssen, J More by this author

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Bibliographic Details

Publisher:: Nature Publishing Group
Journal:: Nature
Volume:: 507
Issue:: 7491
Pages:: 258-261
Publication date:: 2014-01-01
DOI:: 10.1038/nature12971
EISSN:: 1476-4687
ISSN:: 0028-0836

Item Description

Language:: English
Pubs id:: pubs:460530
UUID:: uuid:3e1a59b1-bf02-4e62-8544-4c5b6b614b77
Local pid:: pubs:460530
Source identifiers:: 460530
Deposit date:: 2014-06-17

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Copyright date:: 2014

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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