- Abstract:
-
Secretory vesicle exocytosis is a fundamental biological event and the process by which hormones (like insulin) are released into the blood. Considerable progress has been made in understanding this precisely orchestrated sequence of events from secretory vesicle docked at the cell membrane, hemifusion, to the opening of a membrane fusion pore. The exact biophysical and physiological regulation of these events implies a close interaction between membrane proteins and lipids in a confined spac...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Accepted Manuscript
- Files:
-
-
(pdf, 1.3MB)
-
- Publisher copy:
- 10.1016/j.ceca.2017.10.005
-
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- Publisher:
- Elsevier Publisher's website
- Journal:
- Cell Calcium Journal website
- Volume:
- 68
- Pages:
- 45-61
- Publication date:
- 2017-11-02
- Acceptance date:
- 2017-10-24
- DOI:
- EISSN:
-
1532-1991
- ISSN:
-
0143-4160
- Pubs id:
-
pubs:746133
- URN:
-
uri:3e10edf0-b038-45e2-bb4d-4d61141c0c6b
- UUID:
-
uuid:3e10edf0-b038-45e2-bb4d-4d61141c0c6b
- Local pid:
- pubs:746133
- Language:
- English
- Keywords:
- Copyright holder:
- Elsevier Ltd.
- Copyright date:
- 2017
- Notes:
- © 2017 Elsevier Ltd. All rights reserved. This is the accepted manuscript version of the article. The final version is available online from Elsevier at: https://doi.org/10.1016/j.ceca.2017.10.005
Journal article
Fusion pore in exocytosis: more than an exit gate? A β-cell perspective
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