Blood groups and malaria: fresh insights into pathogenesis and identification of targets for intervention.

Journal article

PURPOSE OF REVIEW: This review summarizes recent advances in our understanding of the interaction between malaria parasites and blood group antigens and discusses how the knowledge gleaned can be used to target the development of new antimalarial treatments and vaccines. RECENT FINDINGS: Studies of the interaction between Plasmodium vivax and the Duffy antigen provide the clearest example of the potential for basic research on blood groups and malaria to be translated into a vaccine that cou...

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Authors: Rowe, J; Opi, D; Williams, T

• Publication status: Published
• Journal: Current opinion in hematology
• Volume: 16
• Issue: 6
• Pages: 480-487
• Publication date: 2009-11-01
• DOI: 10.1097/moh.0b013e3283313de0
• EISSN: 1531-7048
• ISSN: 1065-6251
• Language: English
• Keywords: Drug Administration Routes; Blood Group Antigens; Antigens, Protozoan; Protozoan Proteins; Receptors, Cell Surface; Drug Delivery Systems; Plasmodium; Malaria; Humans