A DNA prime-modified vaccinia virus ankara boost vaccine encoding thrombospondin-related adhesion protein but not circumsporozoite protein partially protects healthy malaria-naive adults against Plasmodium falciparum sporozoite challenge.

Dunachie, S; Walther, M; Epstein, J; Keating, S; Berthoud, T; Andrews, L; Andersen, R; Bejon, P; Goonetilleke, N; Poulton, I; Webster, D; Butcher, G; Watkins, K; Sinden, R; Levine, G; Richie, T; Schneider, J; Kaslow, D; Gilbert, S; Carucci, D; Hill, A

Journal article

A DNA prime-modified vaccinia virus ankara boost vaccine encoding thrombospondin-related adhesion protein but not circumsporozoite protein partially protects healthy malaria-naive adults against Plasmodium falciparum sporozoite challenge.

Abstract:: The safety, immunogenicity, and efficacy of DNA and modified vaccinia virus Ankara (MVA) prime-boost regimes were assessed by using either thrombospondin-related adhesion protein (TRAP) with a multiple-epitope string ME (ME-TRAP) or the circumsporozoite protein (CS) of Plasmodium falciparum. Sixteen healthy subjects who never had malaria (malaria-naive subjects) received two priming vaccinations with DNA, followed by one boosting immunization with MVA, with either ME-TRAP or CS as the antigen...
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Publication status:: Published

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APA Style

Dunachie, S., Walther, M., Epstein, J., Keating, S., Berthoud, T., Andrews, L., Andersen, R., Bejon, P., Goonetilleke, N., Poulton, I., Webster, D., Butcher, G., Watkins, K., Sinden, R., Levine, G., Richie, T., Schneider, J., Kaslow, D., Gilbert, S., … Hill, A. (2006). A DNA prime-modified vaccinia virus ankara boost vaccine encoding thrombospondin-related adhesion protein but not circumsporozoite protein partially protects healthy malaria-naive adults against Plasmodium falciparum sporozoite challenge. Infection and Immunity, 74(10), 5933–5942.

MLA Style

Dunachie, S., et al. “A DNA Prime-Modified Vaccinia Virus Ankara Boost Vaccine Encoding Thrombospondin-Related Adhesion Protein but Not Circumsporozoite Protein Partially Protects Healthy Malaria-Naive Adults against Plasmodium Falciparum Sporozoite Challenge.” Infection and Immunity, vol. 74, no. 10, 2006, pp. 5933–42.

Chicago Style

Dunachie, S, M Walther, J Epstein, S Keating, T Berthoud, L Andrews, R Andersen, et al. 2006. “A DNA Prime-Modified Vaccinia Virus Ankara Boost Vaccine Encoding Thrombospondin-Related Adhesion Protein but Not Circumsporozoite Protein Partially Protects Healthy Malaria-Naive Adults against Plasmodium Falciparum Sporozoite Challenge.” Infection and Immunity 74 (10): 5933–42.
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