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Intravenous and intracoronary fibrinolytic therapy in acute myocardial infarction: overview of results on mortality, reinfarction and side-effects from 33 randomized controlled trials.

Abstract:

During the past 25 years, 24 randomized trials of intravenous (IV) fibrinolytic treatment have been reported, involving a total of some 6000 patients in the acute phase of myocardial infarction. Most tested IV streptokinase (SK), but a few tested IV urokinase (UK). In the past 2 or 3 years numerous small randomized trials of intracoronary (IC) SK have been started, 9 of which, involving a total of about 1000 such patients, have been reported. Because all of these IV and IC trials were small (...

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Publication status:
Published

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Authors


Collins, R More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Trial Service Unit
Furberg, C More by this author
Stampfer, MJ More by this author
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Journal:
European heart journal
Volume:
6
Issue:
7
Pages:
556-585
Publication date:
1985-07-05
EISSN:
1522-9645
ISSN:
0195-668X
URN:
uuid:3d4c088e-10df-476f-9cf5-ee38add50c14
Source identifiers:
42491
Local pid:
pubs:42491

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