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Journal article

Characterising variation in five genetic loci of cytomegalovirus during treatment for congenital infection.

Abstract:

Cytomegalovirus (CMV) is the most common congenital infection in humans and a leading cause of sensorineural hearing loss. Ganciclovir (6 mg/kg twice daily for 42 days) has been shown to reduce hearing deterioration and is used in clinical practice. Vaccines and passive administration of antibody are being evaluated in randomized controlled trials in allograft candidates, women of childbearing age, and pregnant women with primary CMV infection. To help define genetic variation in each of the ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1002/jmv.24654

Authors


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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Paediatrics
Atkinson, C More by this author
Macartney, M More by this author
Conibear, T More by this author
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Publisher:
Wiley Publisher's website
Journal:
Journal of Medical Virology Journal website
Volume:
89
Issue:
3
Pages:
502-507
Publication date:
2016-08-05
Acceptance date:
2016-07-17
DOI:
EISSN:
1096-9071
ISSN:
0146-6615
Pubs id:
pubs:731279
URN:
uri:3d40206b-0e43-4a16-ba74-8eb7c22ea585
UUID:
uuid:3d40206b-0e43-4a16-ba74-8eb7c22ea585
Local pid:
pubs:731279

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