Journal article : Comment
The Lancet Commission on precision health: equitable, data-driven health outcomes for all
- Abstract:
- This review discusses the role of chronic human cytomegalovirus (HCMV) infection in patients receiving immune checkpoint blockade (ICB) treatment against different malignancies, with an especial focus on malignant melanoma. We briefly outline the impact of HCMV infection on the immune system as an entity before exploring its role in the context of cancer. We then address the potential impact on the efficacy of immunotherapeutic agents, particularly ICB, before looking at development of ICB-related autoimmune toxicity. Finally, we discuss potential avenues for future research. This article is part of the discussion meeting issue ‘The indirect effects of cytomegalovirus infection: mechanisms and consequences’.
- Publication status:
- Published
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- Publisher copy:
- 10.1016/s0140-6736(26)00612-4
Authors
- Publisher:
- Elsevier
- Journal:
- Lancet More from this journal
- Publication date:
- 2026-05-25
- Acceptance date:
- 2026-03-26
- DOI:
- EISSN:
-
1474-547X
- ISSN:
-
0140-6736
- Pmid:
-
42184810
- Language:
-
English
- Subtype:
-
Comment
- Pubs id:
-
2427959
- Local pid:
-
pubs:2427959
- Deposit date:
-
2026-06-10
- ARK identifier:
Terms of use
- Copyright holder:
- Elsevier Ltd.
- Copyright date:
- 2026
- Rights statement:
- © 2026 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.
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