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Journal article

Simple sequence repeats in Haemophilus influenzae.

Abstract:

Simple sequence repeat (SSRs) of DNA are subject to high rates of mutation and are important mediators of adaptation in Haemophilus influenzae. Previous studies of the Rd KW20 genome identified the primacy of tetranucleotide SSRs in mediating phase variation (the rapid reversible switching of gene expression) of surface exposed structures such as lipopolysaccharide. The recent sequencing of the genomes of multiple strains of H. influenzae allowed the comparison of the SSRs (repeat units of on...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher version

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Publisher copy:
10.1016/j.meegid.2008.11.006

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Institution:
University of Oxford
Department:
Oxford, MSD, Paediatrics
Role:
Author
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Funding agency for:
Power, PM
Publisher:
Elsevier B.V. Publisher's website
Journal:
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases Journal website
Volume:
9
Issue:
2
Pages:
216-228
Publication date:
2009-03-05
DOI:
EISSN:
1567-7257
ISSN:
1567-1348
URN:
uuid:3d24708d-cae4-413f-b305-75de0e19c6a7
Source identifiers:
218550
Local pid:
pubs:218550

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