Journal article
Efficacy of the MMP inhibitor MMI270 against lung metastasis following removal of orthotopically transplanted human colon cancer in rat.
- Abstract:
-
We have investigated the antitumor effects of synthetic MMP inhibitor MMI270 against postoperative lung metastasis from colon cancer in nude rat. The KM12SM human colon cancer cells were injected into the cecal wall, and at 5 weeks after the injection, the cecum was removed including the tumor. Then, 30 mg/kg of MMI270 was administered perorally twice per day for 2 or 4 weeks, either immediately after removal or after week 2 after the removal. At week 7 after the removal, lung metastasis was ...
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- Publication status:
- Published
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- Publisher copy:
- 10.1002/ijc.21285
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Bibliographic Details
- Journal:
- International journal of cancer. Journal international du cancer
- Volume:
- 118
- Issue:
- 1
- Pages:
- 215-221
- Publication date:
- 2006-01-01
- DOI:
- EISSN:
-
1097-0215
- ISSN:
-
0020-7136
- Source identifiers:
-
226436
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:226436
- UUID:
-
uuid:3d119db6-e939-4c70-8c81-d8bbdfddf3eb
- Local pid:
- pubs:226436
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2006
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