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Journal article

A causal role for brain-derived neurotrophic factor in the homeostatic regulation of sleep.

Abstract:

Slow-wave activity (SWA), the EEG power between 0.5 and 4 Hz during non-rapid eye movement (NREM) sleep, is one of the best characterized markers of sleep need, because it increases as a function of preceding waking duration and decreases during sleep, but the underlying mechanisms remain unknown. We hypothesized that SWA is high at sleep onset because it reflects the occurrence, during the previous waking period, of widespread synaptic potentiation in cortical and subcortical areas. Consiste...

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Journal:
The Journal of neuroscience : the official journal of the Society for Neuroscience
Volume:
28
Issue:
15
Pages:
4088-4095
Publication date:
2008-04-05
DOI:
EISSN:
1529-2401
ISSN:
0270-6474
URN:
uuid:3ce1d160-bb4d-4f44-8c76-40ce7456ee83
Source identifiers:
456115
Local pid:
pubs:456115

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