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Evidence against a specific effect of cholinergic drugs on spatial memory in primates.

Abstract:

A scopolamine-like delay-dependent impairment in spatial delayed response performance in rhesus monkeys was induced by irrelevant interpolated activity or by using extended retention intervals. Physostigmine readily reversed the effects of scopolamine but had no effect on performance in young monkeys performing an irrelevant distractor task or in monkeys tested using extended retention intervals. Reducing stimulus control did not impair performance and did not alter the dose-response curve fo...

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Publication status:
Published

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Authors


Rupniak, NM More by this author
Samson, NA More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Experimental Psychology
Journal:
Behavioural brain research
Volume:
43
Issue:
1
Pages:
1-6
Publication date:
1991-04-05
DOI:
EISSN:
1872-7549
ISSN:
0166-4328
URN:
uuid:3c2c8da1-de42-49eb-8956-0c2042ede918
Source identifiers:
8195
Local pid:
pubs:8195

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