Journal article
CD161-expressing human T cells.
- Abstract:
- Expression of the Natural Killer cell receptor CD161 has recently been identified on a subset of T cells, including both CD4+ T helper and CD8+ T cells. Expression of this molecule within the adult circulation is restricted to those T cells with a memory phenotype. However, the distinct properties of these T cell populations is yet to be fully determined, although expression of CD161 has been related to the secretion of interleukin-17, and therefore to a type 17 phenotype. Recent studies have aimed to determine both the origin of these cells and the significance of CD161 expression as either a marker of specific cell types or as an effector and regulator of lymphocyte function, and hence to characterize the role of these CD161+ cells within a variety of human diseases in which they have been implicated.
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Authors
- Journal:
- Frontiers in immunology More from this journal
- Volume:
- 2
- Issue:
- AUG
- Pages:
- 36
- Publication date:
- 2011-01-01
- DOI:
- EISSN:
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1664-3224
- Language:
-
English
- Keywords:
- Pubs id:
-
pubs:332743
- UUID:
-
uuid:3bb3aba5-6a6e-4fd5-9c7a-c2b18f47b1e2
- Local pid:
-
pubs:332743
- Source identifiers:
-
332743
- Deposit date:
-
2012-12-19
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- Copyright date:
- 2011
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