Journal article
VEGF signals induce trailblazer cell identity that drives neural crest migration.
- Abstract:
-
Embryonic neural crest cells travel in discrete streams to precise locations throughout the head and body. We previously showed that cranial neural crest cells respond chemotactically to vascular endothelial growth factor (VEGF) and that cells within the migratory front have distinct behaviors and gene expression. We proposed a cell-induced gradient model in which lead neural crest cells read out directional information from a chemoattractant profile and instruct trailers to follow. In this s...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Publisher copy:
- 10.1016/j.ydbio.2015.08.011
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Authors
Funding
+ Engineering and Physical Sciences Research Council
More from this funder
Funding agency for:
Schumacher, L
Grant:
EP/F500394/1
Bibliographic Details
- Publisher:
- Elsevier Publisher's website
- Journal:
- Developmental Biology Journal website
- Volume:
- 407
- Issue:
- 1
- Pages:
- 12-25
- Publication date:
- 2015-08-13
- DOI:
- EISSN:
-
1095-564X
- ISSN:
-
0012-1606
- Source identifiers:
-
539603
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:539603
- UUID:
-
uuid:3b996e9d-077b-471d-b47c-f7964811749f
- Local pid:
- pubs:539603
- Deposit date:
- 2016-02-10
Terms of use
- Copyright holder:
- Elsevier
- Copyright date:
- 2015
- Notes:
-
publisher: Elsevier
articletitle: VEGF signals induce trailblazer cell identity that drives neural crest migration
journaltitle: Developmental Biology
articlelink: http://dx.doi.org/10.1016/j.ydbio.2015.08.011
content_type: article
copyright: Copyright © 2015 Elsevier Inc. All rights reserved. © 2015 Elsevier Inc. All rights reserved. This is the accepted manuscript version of the article. The final version is available online from Elsevier at: [10.1016/j.ydbio.2015.08.011]
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