Journal article
HLA*IMP - an integrated framework for imputing classical HLA alleles from SNP genotypes
- Abstract:
-
Motivation: Genetic variation at classical HLA alleles influences many phenotypes, including susceptibility to autoimmune disease, resistance to pathogens and the risk of adverse drug reactions. However, classical HLA typing methods are often prohibitively expensive for large-scale studies. We previously described a method for imputing classical alleles from linked SNP genotype data. Here, we present a modification of the original algorithm implemented in a freely available software suite ...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Publisher copy:
- 10.1093/bioinformatics/btr061
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Authors
Funding
Studienstiftung des deutschen Volkes
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Human Frontier Science Program
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Engineering and Physical Sciences Research Council
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Leverhulme Trust
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Bibliographic Details
- Publisher:
- Oxford University Press Publisher's website
- Journal:
- Bioinformatics Journal website
- Volume:
- 27
- Issue:
- 7
- Pages:
- 968-972
- Publication date:
- 2011-01-01
- DOI:
- EISSN:
-
1460-2059
- ISSN:
-
1367-4803
Item Description
- Language:
- English
- Keywords:
- Subjects:
- UUID:
-
uuid:3b8e377f-8ff5-458a-acbf-f97e3844a9a5
- Local pid:
- ora:6006
- Deposit date:
- 2012-01-11
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Terms of use
- Copyright holder:
- A T Dilthey et al
- Copyright date:
- 2011
- Notes:
- The full-text of this article is not available in ORA, but you may be able to access the article via the publisher copy link on this record page. Citation: Dilthey, A. T. et al. (2011). 'HLA*IMP-an integrated framework for imputing classical HLA alleles from SNP genotypes', Bioinformatics 27 (7), 968-972. [The definitive publisher-authenticated version is available online at: http://bioinformatics.oxfordjournals.org].
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