- Abstract:
- (Figure Presented) Catching up with the curve! The natural curvature found in a majority of a helices has been mimicked in small synthetic oligoamide scaffolds. Differences in hydrogen-bonding patterns in these scaffolds lead to mimetics with varying degrees of curvature in the backbone. This adds another parameter to the structural and functional mimicry of a helices. © 2008 Wiley-VCH Verlag GmbH and Co. KGaA.
- Publication status:
- Published
- Publisher copy:
- 10.1002/anie.200803778
-
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- Journal:
- Angewandte Chemie (International ed. in English)
- Volume:
- 47
- Issue:
- 50
- Pages:
- 9691-9694
- Publication date:
- 2008-01-01
- DOI:
- EISSN:
-
1521-3773
- ISSN:
-
1433-7851
- URN:
-
uuid:3b58d7c0-0765-404c-a16a-a1cdc3faa6de
- Source identifiers:
-
117465
- Local pid:
- pubs:117465
- Language:
- English
- Keywords:
- Copyright date:
- 2008
Journal article
Controlling curvature in a family of oligoamide alpha-helix mimetics.
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