Journal article icon

Journal article

A meta-analysis of temporal changes of response in the placebo arm of surgical randomized controlled trials: an update

Abstract:

Background

Temporal changes in the placebo arm of randomized controlled trials (RCTs) have not been thoroughly investigated, despite the fact that results of RCTs depend on the comparison between arms.

Methods

In this update of our earlier systematic review and meta-analysis, we set out to investigate the effect of assessment time and number of visits on the magnitude of change from baseline in the placebo arm of these trials. We used linear mixed-effects models t...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Files:
Publisher copy:
10.1186/s13063-017-2070-9

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Sub department:
Kennedy Institute for Rheumatology
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Sub department:
Kennedy Institute for Rheumatology
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Sub department:
Kennedy Institute for Rheumatology
Role:
Author
Expand authors...
National Institute for Health Research More from this funder
Publisher:
BioMed Central Publisher's website
Journal:
Trials Journal website
Publication date:
2017-07-01
Acceptance date:
2017-06-27
DOI:
EISSN:
1745-6215
Source identifiers:
707860
Keywords:
Pubs id:
pubs:707860
UUID:
uuid:3b473d98-a35c-4a19-86a9-35c5d2a8a793
Local pid:
pubs:707860
Deposit date:
2017-07-12

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP