Conference item
Inhibition of interleukin-17-induced effects in osteoarthritis - An in vitro study
- Abstract:
-
Interleukin-17A (IL-17) is a pro-inflammator¬y cytokine, which has been reported to be increased in the joint of patients with OA. This study aimed to identify whether IL-17 or its receptors are expressed in the joints of OA patients and establish the effect of IL-17 in vitro on primary human chondrocytes and synovial fibroblasts from the joints of OA patients. We further studied whether any anti-inflammatory agents in current clinical use were able to reduce the effects of IL-17. We hypothes...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
-
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(Accepted manuscript, pdf, 335.1KB)
-
- Publisher copy:
- 10.1016/j.joca.2018.02.258
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Authors
Bibliographic Details
- Publisher:
- Elsevier Publisher's website
- Journal:
- Osteoarthritis and Cartilage Journal website
- Volume:
- 26
- Issue:
- S1
- Pages:
- S118
- Host title:
- Osteoarthritis and Cartilage
- Publication date:
- 2018-04-16
- Acceptance date:
- 2018-01-16
- DOI:
- ISSN:
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1522-9653 and 1063-4584
- Source identifiers:
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856203
Item Description
- Pubs id:
-
pubs:856203
- UUID:
-
uuid:3b395af8-ef76-4f65-bf1b-525a38e1e0c5
- Local pid:
- pubs:856203
- Deposit date:
- 2018-07-26
Terms of use
- Copyright holder:
- Elsevier Ltd
- Copyright date:
- 2018
- Notes:
- © 2018 Published by Elsevier Ltd. This is the accepted manuscript version of the article. The final version is available online from Elsevier at: https://doi.org/10.1016/j.joca.2018.02.258
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