Conference item icon

Conference item

Inhibition of interleukin-17-induced effects in osteoarthritis - An in vitro study

Abstract:

Interleukin-17A (IL-17) is a pro-inflammator¬y cytokine, which has been reported to be increased in the joint of patients with OA. This study aimed to identify whether IL-17 or its receptors are expressed in the joints of OA patients and establish the effect of IL-17 in vitro on primary human chondrocytes and synovial fibroblasts from the joints of OA patients. We further studied whether any anti-inflammatory agents in current clinical use were able to reduce the effects of IL-17. We hypothes...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted Manuscript

Actions


Access Document


Files:
Publisher copy:
10.1016/j.joca.2018.02.258

Authors


More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDORMS
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDORMS
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDORMS
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDORMS
Oxford college:
Keble College
Publisher:
Elsevier Publisher's website
Volume:
26
Issue:
S1
Pages:
S118
Publication date:
2018-04-16
Acceptance date:
2018-01-16
DOI:
ISSN:
1063-4584 and 1522-9653
Pubs id:
pubs:856203
URN:
uri:3b395af8-ef76-4f65-bf1b-525a38e1e0c5
UUID:
uuid:3b395af8-ef76-4f65-bf1b-525a38e1e0c5
Local pid:
pubs:856203

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP