- Abstract:
-
Interleukin-17A (IL-17) is a pro-inflammator¬y cytokine, which has been reported to be increased in the joint of patients with OA. This study aimed to identify whether IL-17 or its receptors are expressed in the joints of OA patients and establish the effect of IL-17 in vitro on primary human chondrocytes and synovial fibroblasts from the joints of OA patients. We further studied whether any anti-inflammatory agents in current clinical use were able to reduce the effects of IL-17. We hypothes...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Accepted Manuscript
- Files:
-
-
(pdf, 335.1kb)
-
- Publisher copy:
- 10.1016/j.joca.2018.02.258
-
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- Publisher:
- Elsevier Publisher's website
- Volume:
- 26
- Issue:
- S1
- Pages:
- S118
- Publication date:
- 2018-04-16
- Acceptance date:
- 2018-01-16
- DOI:
- ISSN:
-
1063-4584 and 1522-9653
- Pubs id:
-
pubs:856203
- URN:
-
uri:3b395af8-ef76-4f65-bf1b-525a38e1e0c5
- UUID:
-
uuid:3b395af8-ef76-4f65-bf1b-525a38e1e0c5
- Local pid:
- pubs:856203
- Copyright holder:
- Elsevier Ltd.
- Copyright date:
- 2018
- Notes:
- © 2018 Published by Elsevier Ltd. This is the accepted manuscript version of the article. The final version is available online from Elsevier at: https://doi.org/10.1016/j.joca.2018.02.258
Conference item
Inhibition of interleukin-17-induced effects in osteoarthritis - An in vitro study
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