- Abstract:
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Genome-wide association studies (GWAS) have found few common variants that influence fasting measures of insulin sensitivity. We hypothesized that a GWAS of an integrated assessment of fasting and dynamic measures of insulin sensitivity would detect novel common variants. We performed GWAS of the modified Stumvoll Insulin Sensitivity Index (ISI) within the Meta-Analyses of Glucose and Insulin-related traits Consortium. Discovery was performed in 16,753 individuals, and replication was attempt...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Accepted manuscript
- Files:
-
-
(pdf, 2.5mb)
-
- Publisher copy:
- 10.2337/db16-0199
-
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- Publisher:
- American Diabetes Association Publisher's website
- Journal:
- Diabetes Journal website
- Publication date:
- 2016-07-14
- Acceptance date:
- 2016-07-05
- DOI:
- ISSN:
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1939-327X and 0012-1797
- Pubs id:
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pubs:635409
- URN:
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uri:3b1318ad-dd5d-4ba6-9d68-f95de140a846
- UUID:
-
3b1318ad-dd5d-4ba6-9d68-f95de140a846
- Local pid:
- pubs:635409
- Language:
- English
- Keywords:
- Copyright holder:
- American Diabetes Association
- Copyright date:
- 2016
- Notes:
- © 2016 by the American Diabetes Association. This is the accepted manuscript version of the article. The final version is available online from the American Diabetes Association at: [10.2337/db16-0199].
Journal article
Genome-wide association study of the modified Stumvoll Insulin Sensitivity Index identifies BCL2 and FAM19A2 as novel insulin sensitivity loci.
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