Journal article
Cytotoxicity Effects and Apoptosis Induction by Bisbenzylisoquinoline Alkaloids from Triclisia subcordata.
- Abstract:
-
Triclisia subcordata Oliv (Menispermeaceae) is a medicinal plant traditionally used for the treatment of various diseases in West Africa. The ethanol extract of T. subcordata and its fractions were screened for in vitro anti-ovarian cancer activities using the Sulforhodamine B assay. The crude alkaloids showed the strongest activity in cell growth assays on Ovcar-8 and A2780 cell lines (IC50 < 2.4 µg/mL). A bisbenzylisoquinoline alkaloid-cycleanine was isolated using HPLC and identified b...
Expand abstract
- Publication status:
- Published
- Peer review status:
- Peer reviewed
Actions
Authors
Funding
Nigerian ETF
More from this funder
Bibliographic Details
- Publisher:
- Wiley Publisher's website
- Journal:
- Phytotherapy Research Journal website
- Volume:
- 30
- Issue:
- 9
- Pages:
- 1533-1539
- Publication date:
- 2016-06-08
- Acceptance date:
- 2016-05-11
- DOI:
- EISSN:
-
1099-1573
- ISSN:
-
0951-418X
- Pmid:
-
27270992
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:627711
- UUID:
-
uuid:3b01bf39-c732-43ad-92e5-c0aad2e7277a
- Local pid:
- pubs:627711
- Source identifiers:
-
627711
- Deposit date:
- 2017-02-20
Terms of use
- Copyright holder:
- Wiley
- Copyright date:
- 2016
- Notes:
-
© 2016 John Wiley and Sons Ltd.
This is the accepted manuscript version of the article. The final version is available online from Wiley at: [10.1002/ptr.5660]
Metrics
If you are the owner of this record, you can report an update to it here: Report update to this record